Acknowledgements

We Thank Christoph Büschl and Mathias Percipalle (Schur Group, Institute of Science and Technology Austria) for their insightful discussions and contributions toward the refinement of these tools. We are particularly grateful to Tom Goddard (University of California, San Francisco) for the release of UCSF ChimeraX version 1.10.dev202502272020, which addressed critical bugs within the Foldseek integration, and for his valuable feedback that helped shape the software's development. Further we want to thank Pim Huis in ‘t Veld (Huis Group, Max Perutz Labs), for discussing the idea of a ΔG Filter for the PDBePISA analysis.

We thank Mariana Pereira Guarda (de Bono Group, Institute of Science and Technology Austria) for her assistance in selecting the color schemes and for her conceptual ideas that directly influenced the implementation of new features. We also thank Ana Chegão for her suggestions regarding the nomenclature of the ChopChop plug-in and Philipp Bauer for his expert guidance in designing the intuitive graphical icons for the toolbar. Finally, we acknowledge the use of large language models, specifically ChatGPT-4 and Gemini 1.5, as computational copilots for scripting and bug identification during the development process.